Granzyme K contributes to endothelial microvascular damage and leakage during skin inflammation.

Christopher T TurnerMatthew R ZeglinskiWendy BoivinHongyan ZhaoMegan A PawlukKatlyn C RichardsonArundhasa ChandrabalanPhillip BirdRithwik RamachandranRoma SehmiHermenio LimaGail GauvreauDavid J Granville

Published in: The British journal of dermatology (2022)

GzmK may provide a potential therapeutic target for skin conditions associated with persistent inflammation, vasculitis and pathological angiogenesis.

Keyphrases

oxidative stress
wound healing
endothelial cells
soft tissue
vascular endothelial growth factor
climate change