Characterization and implications of the dynamics of eosinophils in blood and in the infarcted myocardium after coronary reperfusion.
Cesar Rios-NavarroJose GavaraVeronica VidalClara BonanadPaolo RacugnoAntoni Bayes-GenisGema MiñanaOliver HusserRicardo OltraJulio NuñezFrancisco J ChorroVicente BodiAmparo Ruiz-SauriPublished in: PloS one (2018)
Eosinopenia post-MI was associated with an impaired cardiac structure and adverse events. The decay in circulating eosinophils soon after reperfusion mirrors their migration into the infarcted myocardium, as reflected by their presence in heart samples from swine and patients. Further studies are needed to understanding this unexplored pathway and its therapeutic implications.
Keyphrases
- end stage renal disease
- acute myocardial infarction
- cerebral ischemia
- ejection fraction
- chronic kidney disease
- newly diagnosed
- coronary artery disease
- heart failure
- acute ischemic stroke
- left ventricular
- prognostic factors
- aortic stenosis
- brain injury
- subarachnoid hemorrhage
- percutaneous coronary intervention
- blood brain barrier
- aortic valve