Pyogenic granulomas (PGs) are benign vascular tumors that are commonly found on cutaneous and mucosal surfaces. However, mucosal PGs are rarely found in the urogenital tract. Here, we report a case of PG arising from the urethra in a 68 year-old female. The mass was found during evaluation for vaginal prolapse, excised, and classified as PG by histopathology. Urethral PG has been rarely reported in adults and should be considered in the differential for patients presenting with urethral mass.