Single-energy CT predicts uric acid stones with accuracy comparable to dual-energy CT-prospective validation of a quantitative method.

• Single-energy CT is the first-line diagnostic tool for suspected renal colic. • A single-energy CT method based on the internal urinary stone attenuation distribution can classify urinary stones into uric acid and non-uric acid stones with high accuracy. • This immensely increases the availability of in vivo stone analysis.