Role of T CD4 + cells, macrophages, C-low threshold mechanoreceptors and spinal Ca v 3.2 channels in inflammation and related pain-like symptoms in murine inflammatory models.

Elodie PicardNicolas KerckhoveAmaury FrançoisLudivine BoudieuElisabeth BillardFrédéric Antonio CarvalhoGemma BogardPhilippe GossetJustine BourdierYoussef AissouniEmmanuel BourinetAlain EschalierLaurence DaulhacChristophe Mallet

Published in: British journal of pharmacology (2022)

3.2 channels with pharmacological agents could be an attractive and readily evaluable strategy in clinical trials, to relieve chronic inflammatory pain in patients.

Keyphrases

oxidative stress
chronic pain
clinical trial
end stage renal disease
pain management
induced apoptosis
neuropathic pain
ejection fraction
chronic kidney disease
newly diagnosed
spinal cord
cell cycle arrest
physical activity
cell proliferation
endoplasmic reticulum stress
nk cells
double blind
pi k akt