IL-33/13 Axis and IL-4/31 Axis Play Distinct Roles in Inflammatory Process and Itch in Psoriasis and Atopic Dermatitis.

Khaldon BodoorFiras Al-QarqazLeen Al HeisMahmoud A Alfaqih Ashraf O OweisRowida AlmomaniMotaz A Obeidat

Published in: Clinical, cosmetic and investigational dermatology (2020)

IL-31 is the key mediator for pruritus in both AD and Ps patients. IL-4/31 axis and IL-33/13 axis play distinct roles in the pathogenesis of Atopic dermatitis and Psoriasis. Interleukin serum levels were not correlated with itch and disease severity in both conditions.

Keyphrases

atopic dermatitis
end stage renal disease
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes