PSMA-positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state.

Ryuta Watanabe Masashi MaekawaTakeshi KiyoiMie KurataNoriyoshi MiuraTadahiko KikugawaShigeki HigashiyamaTakashi Saika

Published in: The Prostate (2021)

Our findings revealed the existence of PSMA-positive tumor endothelial cells in human prostate tumors, which enhances tumor angiogenesis in prostate cancer tissues.

Keyphrases

endothelial cells
prostate cancer
pet ct
high glucose
vascular endothelial growth factor
pet imaging
radical prostatectomy
single cell
computed tomography
benign prostatic hyperplasia
induced pluripotent stem cells
positron emission tomography