Drug-induced gingival hyperplasia: a retrospective study using spontaneous reporting system databases.
Haruna HatahiraJunko AbeYuuki HaneToshinobu MatsuiSayaka SasaokaYumi MotookaShiori HasegawaAkiho FukudaMisa NaganumaTomofumi OhmoriYasutomi KinosadaMitsuhiro NakamuraPublished in: Journal of pharmaceutical health care and sciences (2017)
Our results suggest that DIGH monitoring of patients administered immunosuppressants, calcium channel blockers, or anticonvulsants is important. We demonstrated the potential risk of DIGH following the long-term use of calcium channel blocker over approximately 260 days. Based on the results of the association rule mining approach, patients with intellectual disability who are administered phenytoin should be monitored carefully. We recommend that patients who experience symptoms related to DIGH should be closely monitored.
Keyphrases
- drug induced
- intellectual disability
- liver injury
- end stage renal disease
- autism spectrum disorder
- ejection fraction
- newly diagnosed
- adverse drug
- chronic kidney disease
- prognostic factors
- angiotensin converting enzyme
- emergency department
- peritoneal dialysis
- machine learning
- depressive symptoms
- patient reported outcomes
- risk assessment