Treatment response after 6 and 26 weeks is related to baseline glutamate and GABA levels in antipsychotic-naïve patients with psychosis.

Kirsten Borup BojesenBjørn H EbdrupKasper JessenAnne SigvardKaren TangmoseRichard A E EddenHenrik B W LarssonEgill RostrupBrian V BrobergBirte Y Glenthøj

Published in: Psychological medicine (2019)

Glutamatergic and GABAergic abnormalities in antipsychotic-naïve patients appear driven by non-responders to antipsychotic treatment. If replicated, normative reference levels for glutamate and GABA may aid estimation of clinical prognosis in first-episode psychosis patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
patient reported
combination therapy