Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation.
William Bracamonte-BaranNisha A GilotraTaejoon WonKatrina M RodriguezMonica V TalorByoung C OhJan M GriffinIlan WittsteinKavita SharmaJohn SkinnerRoger A JohnsStuart D RussellRobert A AndersQingfeng ZhuMarc K HalushkaGerald BrandacherDaniela CˇihákováPublished in: Circulation. Heart failure (2021)
Loss of graft endothelial PD-L1 expression may play a role in regulating CD8+ T-cell infiltration in human heart transplantation. Murine model results suggest that loss of graft endothelial PD-L1 may facilitate alloresponses and rejection.