Phase II study of durvalumab immediately after completion of chemoradiotherapy in unresectable stage III non-small-cell lung cancer: TORG1937 (DATE study).
Shinji NakamichiKaoru KubotaToshihiro MisumiTetsuro KondoShuji MurakamiYoshimasa ShiraishiHisao ImaiDaijiro HaradaKazutoshi IsobeHidetoshi ItaniSaori TakataKazuyoshi KuwanoYuki MisumiSatoshi IkedaTetsuhiko AsaoNaoki FuruyaShinobu HosokawaYumiko KobayashiYuichi TakiguchiHiroaki OkamotoPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Our study met the primary endpoint. The incidence of pneumonitis was similar to that of a Japanese subset in the PACIFIC study. Our data support the efficacy and safety of durvalumab administered immediately after the completion of CCRT for patients with unresectable stage III NSCLC.