Contrast Clearance Analysis (CCA) to Assess Viable Tumour following Stereotactic Radiosurgery (SRS) to Brain Metastasis in Non-Small Cell Lung Cancer (NSCLC).
Shybi MohamedkhanSumeet HindochaJames de BoisangerThomas MillardLiam WelshPhilip RichAndrew D MacKinnonNicholas WilliamsBhupinder SharmaNicola RosenfelderAnna MinchomPublished in: Cancers (2024)
Our single-centre experience shows CCA to be feasible and useful in patients with NSCLC in cases of diagnostic uncertainty in MRI. It has helped guide treatment in the majority of patients, with subsequent outcomes following the implementation of the treatment based on the results, suggesting correct classification. Recommendations from our experience of the implementation include the careful consideration of the thin rim of the rapid contrast clearance and the timing of the CCA prior to surgery for suspected brain metastasis progression.
Keyphrases
- small cell lung cancer
- magnetic resonance
- primary care
- healthcare
- contrast enhanced
- magnetic resonance imaging
- minimally invasive
- resting state
- machine learning
- deep learning
- pulmonary embolism
- quality improvement
- multiple sclerosis
- cerebral ischemia
- functional connectivity
- tyrosine kinase
- combination therapy
- percutaneous coronary intervention
- diffusion weighted imaging
- loop mediated isothermal amplification
- sensitive detection
- data analysis