Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an N -of-1 clinical trial.

Montaser F ShaheenJulie Y TseEthan S SokolMargaret MastersonPranshu BansalIan RabinowitzChristy A TarletonAndrey Senos DobroffTracey L SmithThèrése J BocklageBrian K MannakeeRyan N Gutenkunst Joyce BischoffScott A NessGregory M RiedlingerRoman GroisbergRenata PasqualiniShridar GanesanWadih Arap

Published in: eLife (2022)

NCT03941782.

Keyphrases

clinical trial
lymph node
copy number
phase ii
single cell
open label
double blind
study protocol
phase iii
gene expression
dna methylation