Radiation Necrosis in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy.

Stephen F KralikC Y HoW FinkeJ C BuchsbaumC P HaskinsC-S Shih

Published in: AJNR. American journal of neuroradiology (2015)

Pediatric patients with brain tumors treated with proton radiation therapy demonstrate a high incidence of radiation necrosis and a short time to development of necrosis. Multiple small areas of necrosis are frequently identified on imaging. Exposure to multiple chemotherapy agents was a significant risk factor associated with radiation necrosis in these patients.

Keyphrases

radiation therapy
risk factors
newly diagnosed
radiation induced
end stage renal disease
locally advanced
ejection fraction
chronic kidney disease
early stage
squamous cell carcinoma
mass spectrometry
photodynamic therapy
fluorescence imaging