Synthesis of Cyclotriveratrylene-Sucrose-Based Capsules.

Łukasz SzyszkaPiotr CmochAleksandra ButkiewiczMykhaylo A Potopnyk Sławomir Jarosz

Published in: Organic letters (2019)

Cyclotriveratrylene (CTV) is a C3-symmetrical macrocycle, which can be used as a chiral building block in the construction of supramolecular containers. Coupling of the CTV unit with a sucrose molecule gave enantiopure water-soluble (after deprotection) containers. The absolute configuration of the synthesized capsules was determined by NMR and ECD spectroscopies and DFT calculations.

Keyphrases

water soluble
density functional theory
molecular dynamics
magnetic resonance
high resolution
molecular dynamics simulations
solid state
room temperature
ionic liquid