Comparison of performances of loop-mediated isothermal amplification, XPERT MTB/RIF and BACTEC MGIT in the diagnosis of childhood tuberculosis.

Achyudhananda Govindan SRakesh YadavPankaj C VaidyaSunil SethiNancy MehraRashmi R DasAastha SainiIndu VermaMeenu Singh

Published in: Journal of paediatrics and child health (2021)

We noted that LAMP-IS6110 performed better than Xpert MTB/RIF (Cepheid) in terms of sensitivity when compared against BACTEC MGIT 960 culture as reference standard, though specificity of both the tests was comparable. The diagnostic performance of BACTEC MGIT 960 culture was better than LAMP-IS6110 and Xpert MTB/RIF in paediatric PTB, when compared against CRS.

Keyphrases

pulmonary tuberculosis
loop mediated isothermal amplification
mycobacterium tuberculosis
sensitive detection
intensive care unit
emergency department
young adults
childhood cancer