A case of aggressive systemic mastocytosis with bulky lymphadenopathy showing response to midostaurin.

Alessandra IurloFabio SerpentiSimona MuratoriValerio PravettoniFabio Massimo UlivieriGiorgio Alberto CrociAnna Chiara MiglioriniAndrea EspositoMaria Cecilia GoldanigaGiorgia Natascia SaporitiGiulia GalassiLuca BaldiniFrancesco OnidaFederica Irene Grifoni

Published in: Clinical case reports (2020)

Management of systemic mastocytosis is an emerging challenge which requires a multidisciplinary diagnostic approach and personalized treatment strategy. Midostaurin can rapidly reduce the disease burden, also in cladribine refractory cases.

Keyphrases

risk factors
combination therapy
drug induced
ultrasound guided