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Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

Sanjay PopatTe-Chun HsiaJen-Yu HungHyun Ae JungJin-Yuan ShihCheol Kyu ParkSeung Hyeun LeeTatsuro OkamotoHee Kyung AhnYong Chul LeeYuki SatoSung Sook LeeCeline MascauxHasan DaoudAngela MärtenSatoru Miura
Published in: The oncologist (2022)
In a real-world setting, EGFR TKIs were the preferred treatment option in patients with uncommon EGFR mutations; strongest outcomes were seen in patients with major uncommon and compound mutations.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • advanced non small cell lung cancer
  • brain metastases
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • adipose tissue
  • combination therapy