Clinical heterogeneity of pediatric hepatocellular carcinoma.

Amber Marie D'Souza Alexander J TowbinAnita GuptaMaria AlonsoJaimie D NathanAlex BondocGreg TiaoJames I Geller

Published in: Pediatric blood & cancer (2020)

Genetic and anatomic predisposing conditions were seen in over half of this cohort. Evans stage 1 or 2 disease was linked to improved survival. LT trended toward improved survival. Use of known chemotherapy agents may benefit a smaller group of pediatric HCC and warrants formal prospective study through cooperative group trials.

Keyphrases

free survival
genome wide
single cell
squamous cell carcinoma
locally advanced
gene expression
copy number
dna methylation
young adults
rectal cancer
childhood cancer