Associations between use of chemical hair products and epigenetic age: Findings from the Sister Study.

Che-Jung ChangKatie M O'BrienJacob K KresovichJamaji C Nwanaji-EnweremZongli XuSymielle A GastonChandra L JacksonDale P SandlerJack A TaylorAlexandra J White

Published in: Environmental epidemiology (Philadelphia, Pa.) (2024)

In this US-based study, we found little evidence of associations between chemical hair product use and epigenetic age in Black and non-Hispanic White women. Observed associations were modest and largely not supported by dose-response relationships or were inconsistent across epigenetic age measures. Previously observed associations between chemical hair product use and aging-related health outcomes may not be explained by the biological aging pathways captured by DunedinPACE, GrimAgeAccel, or PhenoAgeAccel. Alternative biological pathways are worth investigating in racially diverse samples.

Keyphrases

dna methylation
gene expression
polycystic ovary syndrome
type diabetes
metabolic syndrome
pregnant women
pregnancy outcomes
drug induced