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Phosphinoyl Radical Initiated Vicinal Cyanophosphinoylation of Alkenes.

Pei-Zhi ZhangLing ZhangJian-An LiAdedamola ShoberuJian-Ping ZouWei Zhang
Published in: Organic letters (2017)
A double-functionalization reaction of alkenes through Mn(OAc)3-mediated phosphinoyl radical addition followed by CuCN-catalyzed cyanation is introduced. This one-pot reaction is performed under mild conditions to afford vicinal cyanophosphinoylation products.
Keyphrases
  • room temperature
  • electron transfer