Disease-modifying interactions between chronic kidney disease and osteoarthritis: a new comorbid mouse model.

Sohel M JuloviAiken DaoKatie TrinhAlexandra K O'DonohueCindy ShuSusan SmithMeena ShingdeAaron SchindelerNatasha M RogersChristopher B Little

Published in: RMD open (2023)

This study assessed a world-first preclinical comorbid CKD-OA model. Our findings demonstrate significant bidirectional disease-modifying interaction between CKD and OA.

Keyphrases

chronic kidney disease
end stage renal disease
mouse model
knee osteoarthritis
stem cells
bone marrow
peritoneal dialysis