Login / Signup

Growth Temperature, Trehalose, and Susceptibility to Heat in Mycobacterium avium.

Simonne GuenetteMyra D WilliamsJoseph O Falkinham Iii
Published in: Pathogens (Basel, Switzerland) (2020)
Mycobacterium avium is capable of an adaptive, reversible response to high-temperature survival depending on its growth temperature. Trehalose concentrations of M. avium cells grown at 42 °C were significantly higher compared to those of cells grown at 25 °C. Further, the survival of cells of M. avium grown at 42 °C and exposed to 65 °C were significantly higher than the survival of cells grown at 25 °C. This adaptive response to growth temperature may play a role in the persistence of M. avium in premise plumbing.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • mycobacterium tuberculosis
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • oxidative stress
  • free survival