Exacerbation Frequency And Eosinophil Counts Among Patients With COPD Currently Prescribed Triple Therapy.
Victoria S BensonKatie C PascoeJames SiddallMark SmallHana MullerovaPublished in: International journal of chronic obstructive pulmonary disease (2019)
This analysis demonstrates that there is a subpopulation of patients with COPD who continue to experience exacerbations despite receiving triple therapy; approximately three-quarters of these had eosinophils ≥150 cells/μL and one-third had eosinophils ≥300 cells/μL; these patients may benefit from eosinophil-targeted therapies.
Keyphrases
- chronic obstructive pulmonary disease
- induced apoptosis
- cell cycle arrest
- end stage renal disease
- lung function
- ejection fraction
- newly diagnosed
- chronic kidney disease
- cystic fibrosis
- signaling pathway
- cell death
- prognostic factors
- peritoneal dialysis
- cell proliferation
- patient reported outcomes
- air pollution
- pi k akt
- acute respiratory distress syndrome
- chronic rhinosinusitis