Profiling of gastric cancer cell-surface markers to achieve tumour-normal discrimination.

Judith TohMichal Marek HoppeTeena ThakurHenry YangKar Tong TanBrendan PangSharmaine HoRony RoyKhek Yu HoKhay Guan YeohPatrick TanRaghav Sundar Anand D Jeyasekharan

Published in: BMJ open gastroenterology (2021)

CEAMCAM5, CEACAM6, EpCAM, and CA72-4 form a versatile set of markers for robust discrimination of GC from adjacent normal tissue. As cell-surface markers, they are compatible with both IHC and live imaging approaches. These candidates may be exploited to improve automated identification of tumour tissue in GC.

Keyphrases

cell surface
high resolution
machine learning
high throughput
deep learning
gas chromatography
photodynamic therapy
tandem mass spectrometry