Predictors of Humoral Response to SARS-CoV-2 Vaccination after Hematopoietic Cell Transplantation and CAR T-cell Therapy.
Roni TamariIoannis PolitikosDavid A KnorrSantosha A VardhanaJennifer C YoungLeeAnn Tan MarcelloSital DoddiSean M DevlinLakshmi V RamanathanMelissa S PessinErica DunnMeighan PalazzoChristina D BravoGenovefa A PapanicolaouMini KambojMiguel-Ángel PeralesDavid J ChungGunjan L ShahPublished in: Blood cancer discovery (2021)
Identifying predictors of response to vaccination against SARS-CoV-2 in patients following cellular therapy is critical to managing this highly vulnerable patient population. To date, this is the most comprehensive study evaluating quantitative and qualitative responses to vaccination, providing parameters most predictive of response and potentially informing booster vaccination strategies.See related article by Chung et al., p. 568. This article is highlighted in the In This Issue feature, p. 549.