Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.
Nancy H C LoosViët BuiDaniëlle H de JongMaria C LebreHilde RosingJos H BeijnenAlfred H Schinkel
Published in: Cancer chemotherapy and pharmacology (2024)
These results suggest that delayed loperamide administration can be added to ritonavir-boosted oral docetaxel treatment, without affecting the overall systemic exposure of docetaxel.