Noninvasive Ventilation for Preoxygenation during Emergency Intubation.
Kevin W GibbsMatthew W SemlerBrian E DriverKevin P SeitzSusan B StempekCaleb TaylorDaniel Resnick-AultHeath D WhiteSheetal GandotraKevin C DoerschugAmira MohamedMatthew E PrekkerAkram KhanJohn P GaillardLuke AndreaNeil R AggarwalJason C BrainardLuAnn H BarnettStephen J HallidayVeronika BlinderAlon DaganMicah R WhitsonSteven G SchauerJames E WalkerAndrew B BarkerJessica A PalakshappaAmelia MuhsJoanne M WozniakPatrick J KramerCori WithersShekhar A GhamandeDerek W RussellAndrei SchwartzAri MoskowitzSydney J HansenGopal AlladaJordan K GoransonDaniel G FeinPeter D SottileNicholas KellyShannon M AlwoodMicah T LongRishi MalhotraNathan I ShapiroDavid B PageBrit J LongChristopher B ThomasStacy A TrentDavid R JanzTodd W RiceWesley H SelfVikhyat S BebartaBradley D LloydJillian RhoadsKelsey WomackBrant ImhoffAdit A GindeJonathan D Caseynull nullPublished in: The New England journal of medicine (2024)
Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. (Funded by the U.S. Department of Defense; PREOXI ClinicalTrials.gov number, NCT05267652.).