Predictive factors for resection and survival in type A borderline resectable pancreatic ductal adenocarcinoma patients after neoadjuvant therapy: A retrospective cohort study.
Luis SecanellaJuli BusquetsNúria PeláezMaría SorribasBerta LaquenteSandra RuizThiago CarnavalSebastián VidelaJuan FabregatPublished in: Medicine (2022)
Patients with BR-PDAC have a high risk for a margin-positive resection. Serum Carbohydrate Antigen 19-9 plasmatic levels and vascular involvement stand out as disease-related prognostic factors.This study will provide valuable information on the prognostic factors associated with resection. We will exclude locally advanced tumors and expect this approach to provide more realistic resection rates without selecting those patients that undergo surgical exploration. However, focusing on an anatomical definition may limit the results' generalizability.
Keyphrases
- prognostic factors
- locally advanced
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- rectal cancer
- squamous cell carcinoma
- peritoneal dialysis
- healthcare
- radiation therapy
- stem cells
- neoadjuvant chemotherapy
- mesenchymal stem cells
- patient reported outcomes
- cell therapy
- smoking cessation