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Anaemia among females in child-bearing age: Relative contributions, effects and interactions of α- and β-thalassaemia.

Sachith MettanandaMarius SuranjanRoshale FernandoTiran DiasChamila MettanandaRexan RodrigoLakshman PereraRichard GibbonsAnuja PremawardhenaDouglas Higgs
Published in: PloS one (2018)
Nearly one third of anaemic females in child bearing age had thalassaemia trait of which α-thalassemia contributes to a majority. Both α- and β-thalassaemia trait can co-exist and have ameliorating effects on red cell indices in heterozygous states. α-Thalassaemia trait was significantly associated with premature births and low birth weight. It is of paramount importance to investigate the causes of anaemia in women of child bearing age and during pregnancy in addition to providing universal iron supplementation.
Keyphrases
  • low birth weight
  • mental health
  • genome wide
  • preterm infants
  • iron deficiency
  • human milk
  • preterm birth
  • single cell
  • early onset
  • type diabetes
  • gene expression
  • metabolic syndrome
  • mesenchymal stem cells
  • skeletal muscle