Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses.
Thomas H A EderveenGerben FerwerdaInge M AhoutMarloes VissersRonald de GrootJos BoekhorstHarro M TimmermanMartijn A HuynenSacha A F T van HijumMarien I de JongePublished in: Microbiome (2018)
The nasopharyngeal microbiota in young infants with RSV infection is marked by an overrepresentation of the genus Haemophilus. We present that this bacterium is associated with viral load and mucosal CXCL8 responses, both which are involved in RSV disease pathogenesis.