Toxoplasma gondii IgG Serointensity Is Positively Associated With Frailty.
Hira MohyuddinBlanca LaffonJoão P TeixeiraSolange CostaArmanda Teixeira-GomesEduardo PásaroNiel ConstantineAline DagdagHeidi K OrtmeyerBoris TizenbergLiubov AframPoyu YenChristopher MaranoChristopher A LowryAndrew J HoisingtonJill A RachBeiselVanessa ValdiglesiasCarlota Lema-ArranzNatalia Fernández-BertólezAna MasedaJosé C Millán-CalentiElizabeth J KovacsJohanna M GostnerDietmar FuchsLisa A BrennerLaura Lorenzo-LópezTeodor T PostolachePublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
This first reported association between T. gondii and frailty is limited by a cross-sectional design and warrants replication. While certain biomarkers of inflammaging were associated with both T. gondii IgG serointensity and frailty, they did not fully mediate the T. gondii-frailty association.
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