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Heavy Prenatal Alcohol Exposure is Related to Smaller Corpus Callosum in Newborn MRI Scans.

Sandra W JacobsonJoseph L JacobsonChristopher D MoltenoChristopher M R WartonPia WintermarkH Eugene HoymeGreetje De JongPaul TaylorFleur WartonNadine M LindingerR Colin CarterNeil C DodgeEllen GrantSimon K WarfieldLilla ZölleiAndré J W van der KouweErnesta M Meintjes
Published in: Alcoholism, clinical and experimental research (2017)
Given that midline craniofacial anomalies have been recognized as a hallmark of fetal alcohol syndrome in humans and animal models since this syndrome was first identified, the CC deficit identified here in newborns may support early identification of a range of midline structural impairments. Smaller CC during the newborn period may provide an early indicator of fetal alcohol-related cognitive deficits that have been linked to this critically important brain structure in childhood and adolescence.
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