Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP.

Xiaogang ShenMengnan LiYawen LiYuning JiangKunxu NiuShixiong ZhangXuan LuRuntao ZhangZhiqin ZhaoLiangxing ZhouZhifang GuoSiwei WangCong WeiLiping ChangYunlong HouYi-Ling Wu

Published in: Chinese medicine (2024)

BZBS has the potential to alleviate inflammation in metabolic organs of naturally aged mice and maintain metabolic homeostasis. This study presents novel clinical therapeutic approaches for the prevention and treatment of age-related metabolic diseases.

Keyphrases

oxidative stress
mouse model
metabolic syndrome
climate change
high fat diet induced