Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine.
Tomohiro FukudaMakoto NaganumaKaoru TakabayashiYuya HagiharaShun TanemotoEna NomuraYusuke YoshimatsuShinya SugimotoKosaku NankiShinta MizunoYohei MikamiKayoko FukuharaTomohisa SujinoMakoto MutaguchiNagamu InoueHaruhiko OgataYasushi IwaoTakayuki AbeTakanori KanaiPublished in: Journal of gastroenterology and hepatology (2020)
The present study showed that mucosal Ac-5-ASA concentrations, as well as 5-ASA concentrations, are higher in UC patients with endoscopic remission. Ac-5-ASA may be useful for a biomarker of 5-ASA efficacy.