Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19.
Guillaume MiltgenThomas GarrigosPascal CholleyMarine DeleumeNicolas AllouJérôme AllynDavid A WilkinsonNathalie LugagneOlivier BelmonteXavier BertrandDidier HocquetPatrick MavinguiPublished in: Antimicrobial resistance and infection control (2021)
Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two main factors may have contributed to cross-transmission: misuse of gloves and absence of change of personal protective equipment, in the context of COVID-19-associated shortage. This work highlights the importance of maintaining infection control measures to prevent CPE cross-transmission despite the difficult context and that this type of outbreak can potentially involve several species of Enterobacterales.
Keyphrases
- sars cov
- acinetobacter baumannii
- drug resistant
- multidrug resistant
- klebsiella pneumoniae
- intensive care unit
- gram negative
- escherichia coli
- respiratory syndrome coronavirus
- coronavirus disease
- end stage renal disease
- pseudomonas aeruginosa
- ejection fraction
- newly diagnosed
- chronic kidney disease
- mechanical ventilation
- patient reported outcomes
- prognostic factors
- cystic fibrosis
- crispr cas
- staphylococcus aureus
- methicillin resistant staphylococcus aureus