Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT 2B R/β-arrestin2 pathway.
Yinquan FangXiao DingYihe ZhangLei CaiYuan GeKaiyang MaRong XuShanshan LiMengmeng SongHong ZhuJiaqi LiuJianhua DingMing LuGang HuPublished in: Journal of neuroinflammation (2022)
R/β-arrestin2 pathway in a mouse model of MDD and provide a novel therapeutic avenue for MDD.