Molecular action mechanism of anti-inflammatory hydrolysates obtained from brewers' spent grain.
Raúl E CianCristina Hernández-ChirlaqueReyes Gámez-BelmonteSilvina R DragoFermín Sánchez de MedinaOlga Martínez-AugustinPublished in: Journal of the science of food and agriculture (2020)
BSG hydrolysates, like those obtained from other food sources, regulate the immune response, involving TLR2 and TLR4 and the activation of NFκB and MAPKs, an effect partly maintained after in vitro gastrointestinal digestion. Our data support the hypothesis of a shared, rather unspecific, mechanism of action of protein hydrolysates. © 2020 Society of Chemical Industry.