Transcriptomic evaluation of skin tape-strips in children with allergic asthma uncovers epidermal barrier dysfunction and asthma-associated biomarkers abnormalities.

Ester Del Duca Dante Dahabreh Madeline Kim Johnathan Bar Joel Correa da Rosa Grace Rabinowitz Paola Facheris Pedro Jesús Gómez Arias Annie Chang Vivian Utti Amira Chowdhury Ying Liu Yeriel D Estrada Alexandru Laculiceanu Ioana Agache Emma Guttman-Yassky

Published in: Allergy (2024)

Tape-strips detected epithelial barrier and asthma-associated signatures in normal-appearing skin from children with allergic asthma and may serve as an alternative to invasive approaches for evaluating asthma endotypes.

Keyphrases

allergic rhinitis
chronic obstructive pulmonary disease
lung function
young adults
cystic fibrosis
wound healing
oxidative stress
gene expression
soft tissue