Neurological-related proteomic profiling in plasma of children with metabolic healthy and unhealthy overweight/obesity.
Marcos Olvera-RojasAbel Plaza-FloridoPatricio Solís-UrraFrancisco J Osuna-PrietoFrancisco B OrtegaPublished in: Pediatric obesity (2024)
Our proteomics study suggests that cardiometabolic health (represented by MHO/MUO or individual MS markers) is associated with the concentration in plasma of several proteins involved in brain health. Larger-scale studies are needed to contrast/confirm these findings, with CD38 standing out as a particularly noteworthy and robust discovery.
Keyphrases
- young adults
- healthcare
- public health
- mass spectrometry
- weight loss
- mental health
- weight gain
- health information
- insulin resistance
- type diabetes
- multiple sclerosis
- small molecule
- magnetic resonance
- label free
- ms ms
- resting state
- cerebral ischemia
- body mass index
- adipose tissue
- high fat diet induced
- case control
- functional connectivity
- human health