Searching for plant-derived antivirals against dengue virus and Zika virus.
Emerson de Castro BarbosaTânia Maria Almeida AlvesMarkus KohlhoffSoraya Torres Gaze JangolaDouglas Eduardo Valente PiresAnna Carolina Cançado FigueiredoÉrica Alessandra Rocha AlvesCarlos Eduardo Calzavara-SilvaMarcos SobralErna Geessien KroonLuiz Henrique RosaCarlos Leomar ZaniJaquelline Germano de OliveiraPublished in: Virology journal (2022)
Our results showed that plant extracts, especially those from the Hippeastrum genus, can be a valuable source of antiviral compounds against ZIKV and DENV-2. The majority of compounds identified have never been previously described for their activity against ZIKV and other viruses.