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Vitamin C Deficiency Causes Cell Type-Specific Epigenetic Reprogramming and Acute Tubular Necrosis in a Mouse Model.

Zihui YuZiying XuYuan LiangPengbin YinYue ShiJiayi YuJunfeng HaoTing WangWeimin Ci
Published in: Journal of the American Society of Nephrology : JASN (2022)
Vitamin C played a critical role in renal homeostasis and pathogenesis in a mouse model, suggesting vitamin supplementation may be an approach to lower the risk of kidney injury.
Keyphrases
  • mouse model
  • liver failure
  • dna methylation
  • respiratory failure
  • gene expression
  • replacement therapy
  • hepatitis b virus
  • intensive care unit