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Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Clinical Isolates from Aspergillus Section Circumdati .

Sebastien ImbertAnne-Cecile NormandD CostaF GabrielL LachaudC SchuttlerS CassaingC MahincL HasseineM DemarS BrunC BonnalA Moreno-SabaterP BeckerR PiarrouxArnault Fekkar
Published in: Antimicrobial agents and chemotherapy (2023)
The clinical involvement and antifungal susceptibility of Aspergillus section Circumdati are poorly known. We analyzed 52 isolates, including 48 clinical isolates, belonging to 9 species inside the section Circumdati . The whole section exhibited, by the EUCAST reference method, a poor susceptibility to amphotericin B, but species/series-specific patterns were observed for azole drugs. This underlines the interest in getting an accurate identification inside the section Circumdati to guide the choice of antifungal treatment in clinical practice.
Keyphrases
  • candida albicans
  • clinical practice
  • genetic diversity
  • high resolution
  • decision making
  • cell wall