Deciphering Epigenetic Backgrounds in a Korean Cohort with Beckwith-Wiedemann Syndrome.

Hwa Young Kim Choong-Ho Shin Young Ah Lee Chang Ho Shin Gu Hwan Kim Jung Min Ko

Published in: Annals of laboratory medicine (2022)

Comprehensive molecular analysis of the 11p15.5 region revealed epigenotype-phenotype correlations in our BWS cohort. Bisulfite pyrosequencing can help clarify epigenotypes. Methylation levels were correlated with fetal growth and clinical severity in patients with BWS.

Keyphrases

dna methylation
gene expression
genome wide
case report
single molecule