Detecting macromolecular differences of the CSF in low disability multiple sclerosis using quantitative MT MRI at 3T.
Richard D LawlessColin D McKnightKristin P O'GradyAnna J E CombesBaxter P RogersAtlee A WittMereze VisagieDelaney C HoustonLogan E ProckFrancesca R BagnatoSeth A SmithPublished in: Multiple sclerosis journal - experimental, translational and clinical (2023)
Our findings demonstrate increased CSF macromolecular content in pwRRMS and link CSF macromolecular content with clinical impairment. This highlights the potential role of CSF in processing products of demyelination.