Serum glial fibrillary acidic protein is sensitive to acute but not chronic tissue damage in cerebral small vessel disease.
Thomas GattringerChristian EnzingerDaniela PinterSimon Fandler-HöflerMarkus KneihslMelanie HaideggerSebastian EppingerRina DemjahaArabella BuchmannAndrea JerkovicReinhold SchmidtMichael KhalilPublished in: Journal of neurology (2022)
sGFAP is increased in patients with CSVD-related stroke and correlates with the size of the RSSI. However, sGFAP levels were not related to chronic neuroimaging features or progression of CSVD, suggesting that sGFAP is sensitive to acute but not chronic cerebrovascular tissue changes in this condition.