Long-Term Outcome Following Treatment With Allogeneic Mesenchymal Stem/Stromal Cells for Radiation-Induced Hyposalivation and Xerostomia.
Kathrine Kronberg JakobsenCharlotte Duch LynggaardNatasja PaaskeAmanda-Louise Fenger CarlanderJens KastrupAnne Werner HaugeRobin ChristensenChristian GrønhøjChristian von BuchwaldPublished in: Stem cells translational medicine (2024)
In conclusion, this study is the first to present long-term follow-up outcomes of allogeneic ASC treatment as a therapeutic option for radiation-induced xerostomia. The study found that ASC treatment appears safe, and there were no indications of adverse immune responses at the 3-year follow-up. Further studies are warranted to evaluate the findings in larger settings.