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Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats.

Masao NakasatomiAkito MaeshimaKeiichiro MishimaHidekazu IkeuchiToru SakairiYoriaki KanekoKeiju HiromuraYoshihisa Nojima
Published in: Fibrogenesis & tissue repair (2015)
Long-term BrdU labeling marked some of the proximal tubular cells and enabled us to detect tubular cell migration into the interstitium after UUO. This simple method might be useful to detect EMT in vivo.
Keyphrases
  • cell migration
  • high glucose
  • induced apoptosis
  • epithelial mesenchymal transition
  • cell cycle arrest
  • endothelial cells
  • cell death
  • real time pcr
  • liver fibrosis