Low-dose TNF-α promotes angiogenesis of oral squamous cell carcinoma cells via TNFR2/Akt/mTOR axis.
Shutong LiWenchuan LiuJunze LiuZongcheng YangLiguo ZhangFujiao NiePi-Shan YangHongmei GuoChengzhe YangPublished in: Oral diseases (2023)
TNFR2 Nab counteracts the effect of TNF-α on OSCC cells through the TNFR2/Akt/mTOR axis, indicating that blocking TNFR2 might be a promising strategy against cancer.
Keyphrases
- induced apoptosis
- cell proliferation
- low dose
- signaling pathway
- cell cycle arrest
- rheumatoid arthritis
- papillary thyroid
- endothelial cells
- cell death
- oxidative stress
- high dose
- squamous cell carcinoma
- advanced non small cell lung cancer
- vascular endothelial growth factor
- epidermal growth factor receptor
- lymph node metastasis