Large-scale analysis of post-translational modifications in E. coli under glucose-limiting conditions.
Colin W BrownViswanadham SridharaDaniel R BoutzMaria D PersonEdward M MarcotteJeffrey E BarrickClaus O WilkePublished in: BMC genomics (2017)
Unbiased detection of PTM in MS/MS proteomics data facilitates the discovery of novel modification types and previously unobserved dynamic changes in modification across growth timepoints.
Keyphrases
- ms ms
- label free
- small molecule
- escherichia coli
- mass spectrometry
- electronic health record
- high throughput
- big data
- blood glucose
- liquid chromatography tandem mass spectrometry
- real time pcr
- type diabetes
- metabolic syndrome
- high performance liquid chromatography
- data analysis
- high resolution
- weight loss
- sensitive detection